A common belief is that meta analyses should only be based on results from clinical trials. However, assuming the proper statistical methods are used; meta   Meta analysis in clinical trials; Meta analysis of clinical trial data
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    Excluding patients from the analysis in randomised trials often results in biased estimates of treatment effects, but the  Literature reviews: types of clinical study designs.
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  • Meta analysis in clinical research

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  • Systematic reviews with meta analysis are essential tools to reliably summarize the effectiveness of health interventions. A meta analysis based exclusively on  meta analysis of clinical trial data